Is a definition available yet for the latest Zeus Trojan?
You mean this detection?
http://www.virustotal.com/file-scan/report.html?id=0adc7a96508dff34e5701dc9e386b406f4ea7d363e2bbf22e206b834a5e7855e-1325983248
polonus
since they spread using mail, it should mean all the big vendors get hold of samples quick
at the moment they target US banks…soon we have european version(s)
http://www.infosecisland.com/blogview/19295-FBI-Warns-GameOver.html
How the scheme works: Typically, you receive an unsolicited e-mail from NACHA, the Federal Reserve, or the FDIC telling you that there's a problem with your bank account or a recent ACH transaction. (ACH stands for Automated Clearing House, a network for a wide variety of financial transactions in the U.S.) The sender has included a link in the e-mail for you that will supposedly help you resolve whatever the issue is. Unfortunately, the link goes to a phony website, and once you're there, you inadvertently download the Gameover malware, which promptly infects your computer and steals your banking information.
Thanks, I would like to know if Avast free has the definitions for “Game-Over”. Just curious :
Well, test it. 
Tracking Zeus Variants
http://blogs.norman.com/2012/malware-detection-team/tracking-zeus-variants
Zeus is not one bug…new are released every day
See screen shot, 295 listed on this page more then the screen shot show
Zeus is no longer under development,i guess Avast will be able to detect at least 8/10 samples.
By the way,Game over is a new virus(like spyeye,zeus),used by Carders etc,it’s still very new and still under development as far as i know.